THE ROLE OF VASCULAR-METABOLIC FACTORS ON COGNITIVE IMPAIRMENT WORKSHOP REPORT BY THE CAMPAIGN TO PREVENT ALZHEIMER’S DISEASE AND THE BRAIN WATCH COALITION
Ara S. Khachaturian, Zaven S. Khachaturian
The grand challenge for healthcare systems worldwide is the escalating costs of prolonged care for older people with various chronic disabling disorders. Among these protracted brain incapacitating conditions, progressive deterioration of cognitive functions, different types of dementia, and Alzheimer’s syndrome profoundly impact quality of life, economic and psycho-social, and burdens of family caregivers. This report provides an overview of the deliberations at a think-tank workshop organized by PAD2020 before the AAIC 2022 in July 2022. The participants of this forum included leading experts representing government, academia, industry, and the philanthropic sector. The overarching aim for convening this workgroup (WG) was to seek suggestions for a potential global action plan, a comprehensive public health initiative, aiming for a significant reduction in the incidence of cognitive impairment or dementia-Alzheimer syndrome. The future aim of this undertaking (specifically, the pending task of this WG) is to develop a roadmap for a coordinated large-scale effort to demonstrate the putative efficacy of reducing risks for cognitive impairment/dementia-Alzheimer syndrome via existing interventions for modifiable risks of vascular-metabolic disorders. The primary rationale for such global action plans is that a practical, broad-scale approach to this growing public health crisis problem will substantially reduce the demand and cost for prolonged personalized care of people with dementia. The proposed initiative will require a greater focus on research and investments in therapeutic strategies to delay the onset of cognitive impairment and reduce dementia-related morbidity. Such an approach would emphasize addressing modifiable risks for dementia with affordable, accessible interventions that target modifiable risks for vascular and metabolic disorders likely to result in the most tremendous success.
Ara S. khachaturian ; Zaven S. khachaturian ; ; (2023): The Role of Vascular-Metabolic Factors on Cognitive Impairment Workshop Report by the Campaign to Prevent Alzheimer’s Disease and the Brain Watch Coalition. Vitality, Medicine & Engineering. http://dx.doi.org/10.14283/VME.2023.3